Legacy (NIS + Proteos)

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The Course We've Chosen

TrueCourse brings together two organizations that have earned the trust of leading pharmaceutical and biotechnology companies through decades of scientific partnership.

NanoImaging Services

Founded in 2007 by Bridget Carragher and Clint Potter, both researchers and professors at the Scripps Research Institute, NanoImaging Services was created to help improve access to the emerging power of Transmission Electron Microscopy (TEM). Over nearly two decades, NIS established itself as a leader in cryo-electron microscopy, helping advance hundreds of therapeutic programs with high-resolution structural insights.

By the numbers

  • 200+ 3D structures determined by cryo-EM
  • 70+ membrane proteins solved
  • 220+ AAV samples imaged
  • 3,700+ liposomal samples imaged
  • 2,900+ virus and VLP samples imaged
  • First GMP-compliant cryo-TEM lab in North America (established 2023)

Core strengths

  • Cryo-EM and structural biology
  • Nanoparticle characterization
  • Method validation for regulatory submissions
  • Structure-based drug design support

Proteos

Founded in 2003, Proteos built its reputation on providing high-quality recombinant protein production services to the life-science community. Acquired by NIS in 2025, Proteos operates from laboratories in Kalamazoo, Michigan, with decades of combined scientific experience in protein expression and purification.

Core strengths

  • Recombinant protein expression (mammalian, insect, bacterial)
  • Protein purification
  • Custom antibody production
  • Protein assay services

Stronger Together

Today, those complementary capabilities operate as a single scientific platform with facilities on both coasts and in the Midwest. By integrating protein production with cryo-EM across coordinated workflows, and adding new complementary capabilities, TrueCourse enables a seamless gene-to-structure workflow in 8-12 weeks, eliminating the multi-vendor handoffs that typically add weeks to a project and compromise sample integrity.

Timeline Highlights

2003
2007
2017
2018
2019
2020
2021
2023
2025
Today