Integrated protein production, structural biology, biophysical characterization, and nanoparticle characterization services to accelerate drug discovery.
From producing high-quality recombinant proteins and antibodies to determining 3D structures with cryo-EM, assessing biophysical activity, and characterizing nanoparticle formulations, our team provides critical scientific services seamlessly. Our integrated platform eliminates handoffs between vendors, accelerates timelines, and ensures sample integrity at every stage. With six microscopes on two coasts, protein production laboratories, and 240+ cumulative years of experience, we deliver the data you need to make critical development decisions, quickly.
Service Areas
Protein & Antibody Production
High-quality protein is the foundation of every downstream application. Our comprehensive recombinant protein production services include mammalian cell expression, baculovirus-mediated expression, E. coli expression, as well as antibody production, purification, and assay services.
Core Strengths: Mammalian Cell Expression (HEK293 or CHO); Insect Cell Expression (Baculovirus infected Sf9 or Tni); Bacterial Expression (E. coli); Antibody Production & Purification.
Biophysical Characterization
Measure how your molecules bind, interact, and hold up under stress, giving you the kinetics, affinity, and stability data needed to move confidently from characterization to decision-making. Our SPR, BLI, and DSF/TSA platforms deliver precise interaction and stability data that connects directly to your SAR, lead optimization, and developability workflows.
Core Strengths: Binding Kinetics & Affinity (SPR, BLI); Protein Stability & Formulation (DSF)
Structural Biology
Obtain functional insights into your macromolecules and biologics by visualizing your target's structural components and binding sites. Our advanced cryo-EM workflows deliver 3D protein structures in as little as 2 weeks, accelerating drug design and development.
Core Strengths: Single Particle Analysis, X-ray crystallography, Epitope Mapping.
Nanoparticle Characterization
Cryo-TEM imaging is a vital technique for nanoparticle characterization. Multiple structural attributes, including quantitative and qualitative information, can be assessed from the same dataset. Cryo-TEM and TEM imaging reveal Critical Quality Attributes (CQAs) and structural details that other methods miss, using only a small amount of sample.
Core Strengths: Lipid Nanoparticles (LNPs), Inorganic Nanoparticles, with mRNA, RNA, DNA payloads; Extracellular Vesicles & Exosomes; Virus and VLP samples.
From discovery to IND
We support programs from early discovery through IND filing, providing a seamless workflow across protein production, biophysical characterization, structural biology, and nanoparticle characterization. With 240+ cumulative years of experience and integrated capabilities at our sites across the country, we eliminate the handoffs that slow development timelines.
