Every therapeutic program is defined by two things: the target class you're pursuing and the modality you're using to reach it.
Both require deep molecular and structural understanding to support confident go/no-go decisions, from high-resolution structure determination to biophysical and nanoparticle characterization.
What Defines a Program
Every target class has unique structural questions. Every modality has unique characterization needs.
Most programs do not stall because of limited choices in targets or therapeutic modalities. They stall because the structural and functional relationship between the target and the therapeutic has not been sufficiently characterized. That gap appears later as ambiguity in mechanism of action, unexpected behavior in downstream assays, or delayed go/no-go decisions.
Our team provides protein production, structural biology including cryo-EM and X-ray crystallography, and biophysical characterization capabilities designed to resolve both, generating the structural and biophysical data needed to advance programs at every stage.
Choose Your
TrueCourse
Targets
GPCRs, ion channels, membrane proteins, protein degraders, soluble proteins. What target class are you working in, and what structural questions need to be answered?
Modalities
Vaccines, gene delivery, drug delivery, and novel nanoparticle platforms. What modality-specific characterization does your program require?
