Microscopy Fleet

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Explore our Labs and Instrument Infrastructure

We regularly evaluate new technologies for both our East and West Coast labs to remain at the forefront of the field.

We have six microscopes across our San Diego and Boston sites, including two Titan Krios and four Glacios, offering the most comprehensive industrial access in North America.

Titan Krios vs. Glacios: Side-by-Side Comparison

FeatureTitan Krios (300kV)Glacios (200kV)
Accelerating VoltageUp to 300 kVUp to 200 kV
Electron SourceHigh-brightness field emission gun (FEG)High-brightness field emission gun (FEG)
AutoloaderAutomated cassette loading, up to 12 AutogridsAutomated cassette loading, up to 12 Autogrids
DetectorGatan K3 Direct Detection CameraFalcon 4 Direct Electron Detector
Additional ImagingGatan Bio Quantum Energy FilterNone
Condenser SystemThree-condenser-lens system for automated, continuous, and parallel illuminationStandard condenser system
Drift Rate<1 nm/min<1 nm/min
Best ForHigh-resolution structure determination; rapid, publication-quality data collectionGrid screening, vitrification optimization, nanoparticle characterization
Quantity2 instruments4 instruments
More Info
Mora about Titan Kiros
Mora about Glacios

When to Use Each

Choose Titan Krios when your project demands the highest resolution reconstructions and you need fast, high-throughput data collection for structure determination.

Choose Glacios for earlier-stage work: optimizing sample preparation, screening grids to assess Krios-readiness, characterizing nanoparticle therapeutics and vaccines, or collecting MicroED data.

Our Stats

$24M+

in state-of-the-art TEM Equipment

7,000+

hours per year on Titan Krios Microscopes

23,000+

imaging sessions per year

Our Stats

360+

3D structures determined by cryo-EM

77+

of protein structures solved at 3.5 Å or better resolution

100+

Membrane proteins solved

20+

years of cryo-EM experience