Protein Degraders in Focus: Preparing for Cryo-EM Success

Join Drs. Giovanna Scapin and Lindsey Gottler for a case study of the CRBN-DDB1 complex, both apo and bound to ligand. We present our gene-to-structure workflow, highlighting the importance of generating high-quality, structure-grade CRBN-DDB1 for structural studies of PROTAC complexes.